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Location: Health Sciences Center Time Type: Full time Worker Type: Regular Job Req ID: R106183 Minimum Requirements: Bachelor's degree in Neuroscience, Biomedical Sciences, Physiology or similar. Grade 3 (Hourly) Position Description: The Shin lab in the Department of Anatomical Sciences and Neurobiology at the University of Louisville KY, is accepting applications for a NIH-funded laboratory Research Assistant III. The successful candidate will join an enthusiastic and productive team aimed at investigating how neural circuits are altered in spinocerebellar ataxia type1 (SCA1) and identify brain areas for neuromodulation as a therapeutic strategy. SCA1 is a progressive, debilitating and fatally inherited neurodegenerative disease. The project will employ a SCA1 mouse model undergoing treadmill testing to assess changes in gait performance in a longitudinal study design. In vivo electrophysiological recordings are obtained to reveal how communication in various brain areas contribute to SCA1 motor symptomology with findings informing us on best practice to deliver deep brain stimulation to improve gait dysfunction. Lastly, immunocytochemistry of post-mortem tissue will unmask changes in brain morphology linked to SCA1 pathology and with therapeutic intervention. Overall, this position offers an exciting opportunity for a dedicated and highly motivated individual to contribute to groundbreaking research in neuroscience and contribute significantly to the scientific community. The successful candidate will have the chance to drive innovation and make meaningful contributions to the field. The candidate should also be highly motivated and able to work both independently and as part of a team. Surgical expertise (e.g., stereotaxic implants of recording/stimulating electrodes), behavior testing expertise, managing mouse colonies, genotyping and/or a background in ataxia, and electrophysiology are not required but would be beneficial. Responsibilities...As an office drug collector at Tomo Drug Testing you will experience a fast-paced working environment with a variety of clients. Enjoy learning new skills and being a part of driven team that is making a difference? Want to be a part of a growing company that truly cares...
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